Suriadi (2012), Effectivenness of Indonesian Honney on The Acceleration of C, Article

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Title Effectivenness of Indonesian Honney on The Acceleration of C
Abstract Abstract: The purpose of this study was to investigate the effectiveness of Indonesian honey in wound healing compared to Tegaderm hydrocolloid dressing and Manuka honey. Three groups of male mice were treated to produce 2 circular, full-thickness skin wounds on the dorsum. They were then randomly allocated to receive daily Indonesian honey, Manuka honey, or hydrocolloid (control). Macroscopic findings were observed from day 0 to 14 after wounding. Microscopic findings on days 3, 7, 11, and 14 after wounding were obtained. The ratios of wound areas for honey groups on day 3 were smaller than those of the control group. Wound areas of honey groups gradually decreased to almost the same wound area as the control group on day 14, while the control group wound area peaked on day 5 and rapidly decreased until day 14. On day 3, myofibroblasts and new blood capillaries in wound tissue of honey groups were observed, but were not seen in the control group. After day 7, microscopic findings were almost the same among the 3 groups. These results indicate that Indonesian honey is almost as effective for wound healing as Manuka honey and hydrocolloid dressing.
  1. ,Haryanto
  2. Urai,Tamae
  3. Mukai,Kanae
  4. ,Suriadi
  5. Junko,Sugama
  6. Toshio,Nakatani
Refereed Yes, this version has been refereed
Status Published
Journal or Publications Title WOUNDS
Official URL
Volume 24
Number 4
Page Range 110 to 119
Date 23 April 2012


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